Cardiac retention of [C]HED in genotyped long QT patients: a potential amplifier role for severity of the disease
نویسندگان
چکیده
Alejandro N. Mazzadi,1,2 Xavier André-Fouët,3 Jérôme Duisit,1,2 Véronique Gebuhrer,3 Nicolas Costes,1 Philippe Chevalier,3 Claire Rodriguez,3 Jean-Jacques Schott,4 Hervé Le Marec,4 Pascale Guicheney,5 Didier Le Bars,1 and Marc Janier1,2 1Centre d’Exploration et de Recherche Médicales par Émission de Positons, 69003 Lyon; 2Centre de Recherche et d’Applications en Traitement de l’Image et du Signal, Unité Mixed de Recherche-Centre National de Recherche Scientifique 5515, 69394 Lyon; 3Hôpital Cardiovasculaire et Pneumologique et Université Claude Bernard, 6934 Cedex 03 Lyon; 4Unité 533, Institut National de la Santé et de la Recherche Médicale (INSERM), Unité de Formation et Recherche de Medecine, Hôpital Laënnec, Nantes 44035; and 5Unité 523, INSERM, Institut de Myologie, Groupe Hospitalier Pitié-Salpétrière, Paris 75013, France
منابع مشابه
Cardiac retention of [11C]HED in genotyped long QT patients: a potential amplifier role for severity of the disease.
Although mutations in cardiac sodium and potassium channel genes are associated with congenital long QT syndrome (LQTS), a "modifier" role of the sympathetic nervous system was proposed to explain the distinct severity of the disease. We evaluated cardiac sympathetic innervation using [11C]hydroxyephedrine ([11C]HED) and positron emission tomography (PET) in genotyped LQTS patients. H215O and [...
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تاریخ انتشار 2003